Early sepsis control linked to lower mortality, study finds

Early source control of community-acquired sepsis infections resulted in a decreased risk of death at 90 days, according to a retrospective cohort study published last week in JAMA Surgery. The study found utilizing source control within six hours of sepsis onset was associated with a 29% reduction in the risk-adjusted odds of death at 90 days for the 4,962 patients with sepsis undergoing source control interventions compared with delayed source control of six hours to 36 hours. Quickly identifying the septic foci and starting source control interventions can decrease the number of patients with sepsis who die, the authors concluded. (JAMA Surgery study, 7/13/22)